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Anemia is usually (but not always) the first sign of B12 deficiency

doi: 10.1016/j.jhep.2015.02.008 55 Koca-CaliskanU.YilmazI.TaslidereA.YalcinF

After obtaining favorable results in the investigator-initiated Phase III trial JETALS, and following consultation with Tokushima University, Eisai submitted a new drug application for the treatment of ALS in Japan in January 2024, leading to its approval in September, 2024 and leading to the launch today