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Stigmasterol restores the balance of Treg/Th17 cells by activating the Butyrate-PPARAxis in colitis

2019;316(3):H639H646

Peptides are short chains of amino acids that act as messengers in the body

(1) (5) These hormonal changes also cause the thermoneutral zone to go from a wider temperature range to a narrower one

Stouffer MA, Woods CA, Patel JC, Lee CR, Witkovsky P, Bao L, et al

Activated JNK translocates to mitochondria and phosphorylates anti-apoptotic Bcl-2 family members (e.g., Bcl-2 phosphorylation at serine residues such as Ser70) leading to functional inactivation of Bcl-2/Bcl-xL, and promotes pro-apoptotic conformational changes and mitochondrial translocation of Bax (55, 56)