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In line with this, we observed that inflammatory hotspots under IF are often located around small adipocytes (Fig

The gene expression was normalized using Actin as a reference gene, and the relative expression levels were calculated using the 2 Ct method 59

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Scheller U., Lee C., Seibler P., et al., Impaired Neurogenesis and Synaptogenesis in iPSCderived Parkinson's Patient Cortical Neurons With D620N VPS35 Mutation, BioRxiv (2024), 10.1101/2024.08.07.606995

Specifically, Fe 2+ overload activates the protein kinase B (AKT)/mechanistic target of rapamycin complex 1 (mTORC1) pathway, while also inhibiting the expression of transcription factor EB (TFEB), a master transcriptional regulator of autophagosome-lysosome fusion

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