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Frontiers in Pharmacology (2025) 9

Yang Y, Zhang J, Wu S, Deng Y, Wang S, Xie L

This layered strategy addresses hair loss from multiple angles

Since SIRT1 has antioxidant, anti-inflammatory, and genomic stability effects, and it is highly expressed in microglia and neurons in the human brain (Cho et al

LL-37 offers strong antimicrobial and immunomodulatory effects critical for infected wounds, enhancing tissue repair and angiogenesis [88]

Two other trials, a phase 2 (NCT02017353) and a phase 3 (NCT02099890) study, investigated the effect of Cur on inflammation induced by endometrial carcinoma and spinal cord injury, respectively