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Another study claimed that antioxidants treatment promotes lung cancer by endorsing cell proliferation via decreasing ROS level, DNA damage and inactivation of p53 gene expression [14]

However, not all individuals produce UroA efficiently owing to variations in gut microbiome composition, which has led to the development of direct supplementation strategies to achieve consistent levels across different populations (Reference Singh, DAmico and Andreux11)

On the other hand, mice depleted of dopamine have a complete suppression of REM sleep

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