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Further multicentre randomized studies with simpler inclusion criteria and longer follow-up than those currently available, and eventually evaluation of hard clinical outcomes (that are more closely associated with major clinical events and/or mortality than liver enzymes or insulin levels), are necessary to draw more reliable conclusions

After four weeks at 0.25 milligrams, you increase to 0.5 milligrams for another four weeks

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The warning states that there is an increased risk of suicidal thoughts and behavior in children, adolescents, and young adults who take an antidepressant

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