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It is primarily involved in mood regulation, emotion, and cognition (Arnone et al

Curcumin upregulates the Nrf2 system by repressing inflammatory signaling-mediated Keap1 expression in insulin-resistant conditions

PMC 1470061

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Phytosomes are well suited for oral and topical administration and preparation techniques such as solvent evaporation, rotary evaporation, and lyophilization are commonly employed to bind plant extracts with phospholipids for improved pharmacokinetic properties and targeted therapeutic effects [89, 90]