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The concept of leaky gut refers to compromised intestinal barrier function allowing inappropriate passage of substances into the bloodstream

For example, in the case of ECs, each cell type, either cardiac or vascular, might have a preferential matrix for optimal culturing, and depending on the objective of the study, the microfluidic composition and dynamics must also be adjusted [270]

Likewise, CHE was further reported to activate the MEK/ERK1/2 pathway in a concentrationtime-dependent manner, stimulating the ERK MAPK cascade to induce apoptosis, while P90RSK was found to be a downstream kinase of ERK1/2

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Murdoch, University of Dundee, United Kingdom Reviewed by Kavita Pal, Research and Education in Cancer (ACTREC), India Adriana Sumoza-Toledo, Universidad Veracruzana, Mexico Updates Copyright 2024 Manoharan, Prasad, Pospil and Kzhyshkowska

Hadisaputro, S., Cahyono, B., Suzery, M., Widiastuti, Y., & Iwan Purnawan, A