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Important caveats regarding bacteriostatic water in the UK context: It is not standard in UK clinical practice : Water for Injections BP (single-use) is the norm

The 12mg arm (which produced the 24.2% weight reduction at 48 weeks) followed this retatrutide dosing schedule: Week 1-4: 2mg weekly Week 5-8: 4mg weekly Week 9-12: 8mg weekly Week 13+: 12mg weekly

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These levels were considered feasible within the human population, where 10,000 g B12 capsules are available and would be taken as a single bolus

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