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Moreover, mitochondrial and cytosolic enzymes such as -ketoglutarate dehydrogenase, monoamine oxidase, and glycerol phosphate dehydrogenase are endogenous sources of superoxide anion (O 2 - ) production under pathological conditions [43, 44]

Neuroprotection in acute stroke: targeting excitotoxicity, oxidative and nitrosative stress, and inflammation

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Additionally, some reduce inflammation and oxidative stress in muscle tissue, further supporting endurance, strength and overall muscle performance

[DOI] [PMC free article] [PubMed] [Google Scholar] 13.Animal Care and Use Program, Duke University and Medical Center