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Age-related changes in gastric function can reduce food-bound B12 absorption whilst synthetic supplement absorption remains adequate

High-dose oral cyanocobalamin (1,000 mcg daily) or intramuscular hydroxocobalamin injections are the preferred supplementation routes, as both bypass the need for intrinsic factor

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Angiopoietins regulate vascular reactivity after haemorrhagic shock in rats through the Tie2-nitric oxide pathway

Ozempic itself is FDA-approved for diabetes and (as Wegovy) for weight loss

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