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Sambon M, Wins P, Bettendorff L (2021) Neuroprotective effects of thiamine and precursors with higher bioavailability: focus on benfotiamine and dibenzoylthiamine

Abstract Uncontrolled oxidative stress, reported in Salmonella and HIV infections, colorectal cancer or severe acute malnutrition, has been associated with anaerobic gut microbiome alteration, impaired butyrate production, mucosal immunity dysregulation and disruption of host-bacterial mutualism

The Necessity of the Break: The Washout Period The break, or washout period, is as critical as the administration phase

Traditional herbal medicines have also shown promise in ferroptosis inhibition

Future studies should integrate multi-omics technologies such as transcriptomics and proteomics to further elucidate the molecular mechanisms by which TLYY modulates the gut microbiota-metabolism axis, thereby advancing integrated traditional Chinese and Western medicine strategies for the treatment of ulcerative colitis

Accessed 2/23/2024