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Certain metallic cations, such as copper (Cu) and iron (Fe 2+/3+ ) may contribute significantly to the generation of ROS

Otherwise, supplementation will merely mitigate the damage done

NAC was administered after TNBS+ethanol treatment at the point of maximal GSH decrease (4 hours, Fig

661,662 Astrotauopathies result in astrocytes with various morphotypes classified as (i) astrocytic plaques, (ii) tufted astrocytes, (iii) ramified astrocytes, (iv) globular astroglial inclusions, (v) thorn-shaped astrocytes and (vi) granular/fuzzy astrocytes (Fig

While iron-based Fenton reactions produce hydroxyl radicals (OH), their effectiveness requires an acidic environment, prompting exploration of metals like Mn and Cu that offer superior catalytic performance [76]