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N-Acetyl Epithalon is a synthetic acetylated tetrapeptide (Ac-Ala-Glu-Asp-Gly) with N-terminal acetylation of the parent Epithalon (AEDG) sequence

MG, through its role in the development of AGEs, contributes to vascular damage

Competing interests The authors Thalles Fernando Rocha Ruiz, Patrcia Simone Leite Vilamaior, Vera Aparecida de Oliveira Tiera and Sebastio Roberto Taboga declare they have no financial interests

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The His-Ub conjugates were purified by Ni-NTA beads and resuspended in Laemmli for western blotting