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In 2007, Christopher and colleges analyzed recent IKK inhibitors, e.g

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The traditional Chinese medicine Houttuynia cordata thunb decoction alters intestinal barrier function via an EGFR dependent MAPK (ERK1/2) signalling pathway

However, trichloroethylene and tetrachloroethylene are metabolized mainly by cytochrome P450s, and only a small portion is metabolized by GSTs (e.g., Koob and Dekant, 1991), principally GSTA1-1 (Cummings et al., 2000)