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International Journal of Peptide Research and Therapeutics , 29 (4)

Reviewing the effects of L-leucine supplementation in the regulation of food intake, energy balance, and glucose homeostasis

& Duan, L

OOAC models have been employed to study various vascular diseases such as atherosclerosis, thrombosis, pulmonary arterial hypertension, and others as extensively reviewed by Amid Shakeri et al

In summary, the mechanism of 4-OH-E 1 s neuroprotective effect has two main elements: ( 1 ) 4-OH-E 1 protects neuronal survival by altering the function of p53 through promoting its translocation from nucleus to cytoplasm, thereby reducing its transcriptional activity and the expression of its downstream target genes (including GADD45)

Funding This work was supported by National Science Basic Research Program of Shaanxi and Basic Research Program of Xian Municipal Health Commission (Nos