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10.3390/pharmaceutics14122674 99 PiacentinoD.BianchiE.De DonatisD.FlorioV.ConcaA

Campisi (2005) proposed that specific gene upregulated during senescence and proteins translated from these genes may alter cellular functions and tissue structures

Beyond sleep, glycine also modulates glutamate, helping to balance excitatory and inhibitory neurotransmission, a core mechanism in anxiety and mood regulation: Animal studies suggest thatit reduces corticosterone, a key stress hormone

Induction of COX-2 expression within Th17 cells is triggered by IL-23, facilitating the synthesis of Prostaglandin E2 (PGE2), a byproduct of arachidonic acid metabolism

The slides were mounted with a solution containing DAPI (Molecular Probes) and imaged using a Leica TCS SP8 laser scanning confocal microscope (Leica Microsystems CMS GmbH, Wetzlar, Germany)