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This syndrome involves an unexpected worsening of TB symptoms and clinical manifestations following the initiation of ART

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Prior to infection, normal RBCs were exposed to 20 M homocysteine (HCy-RBCs) for four hours and incubated at 37 C

3:718 10.1038/ncomms1722 [DOI] [PMC free article] [PubMed] [Google Scholar] Raimundo N

However, using variants that do not dimerize, it has been recently described that homodimer formation of GCL is not required for enzyme activation (Yang et al., 2019)

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