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Lui F, Khan Suheb M, Patti L

J Incl Phenom Macrocycl Chem 37:6774

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Notably, the expression of B-cell lymphoma 2 (Bcl-2) was significantly downregulated, leading to apoptosis of spermatocytes [108]

Basing that, we assumed this discrepancy stemmed from the inability of co-culture system in vitro to fully simulate in vivo cellular communication dynamics, and which may be caused by the low concentration of interleukins from original pyroptotic hepatocytes in the co-culture system, which was insufficient to drive M1 polarization of macrophages

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