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Similarly, examining how acute and/or repeated applications of neuropeptides affect expression of mucins (e.g., muc5AC, muc5B) in asthma, COPD, and CF would reveal a potentially causative role for neuropeptides in airway mucus phenotypes

Clinical and Preclinical Dose Ranges in Published Research Most Dihexa research uses rodent models, with doses scaled allometrically to approximate human-equivalent exposures

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Fifty-four male SpragueDawley rats weighing 225300 g (Hana Laboratories) were used in this study

Clinical trials have shown that 33.3% of participants achieved at least a 5% weight loss with 1.2 mg of ecnoglutide, compared to only 3.0% in the placebo group