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The 2023 international guideline supports metformin for adults with PCOS and BMI 25 kg/m for metabolic outcomes, but inositol is a reasonable alternative or adjunct for women who don't tolerate metformin or prefer a non-pharmaceutical option

Available from: Zhang Y, Liu W, Wang Q

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Furthermore, -tocopherol constrains the degree of lipid peroxidation by reducing peroxyl radicals to hydroperoxides (Fig

Jia, D., Wang, Q., Qi, Y., Jiang, Y., He, J., Lin, Y., Sun, Y., Xu, J., Chen, W., Fan, L., Yan, R., Zhang, W., Ren, G., Xu, C., Ge, Q., Wang, L., Liu, W., Xu, F., Wu, P., & Wang, L

On the contrary, proteins that have undergone mild oxidation are highly susceptible to proteasomal degradation due to exposure to hydrophobic amino acids by unfolding targeted protein domains