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Mahmoudiasl GR, Abbaszadeh HA, Rezaei-Tavirani M, Abdollahifar MA, Sadeghi Y, Khoramgah MS, et al

Interestingly, triptolide is found to enhance the sensitivity of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) in pancreatic cancer cells by autophagy activation through Pumilio RNA-binding family member 1 (PUM1) downregulation, suggesting a potential strategy to increase tumor sensitivity to TRAIL [995]

Results TNBS Depletes GSH and Generates ROS In Vitro Although, the induction of colitis by TNBS administration is a well defined model of IBD commonly used to uncover pathophysiological factors, the interaction between GSH and TNBS, remains unknown

Therefore, the development of drugs that target common points of these crosstalk pathways is a novel approach to antagonize cisplatin-induced ototoxicity without affecting antineoplastic efficacy

Vukelic, M., Li, Y

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