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10.1016/j.freeradbiomed.2008.12.018 Free Radic

Methylation plays an essential role in controlling depression by simultaneously increasing the levels of several neurotransmitters that are deficient in depressed patients

Studies have shown that Mn induced S-nitrosylation of PINK1, resulting in the repression of PINK1/parkin-mediated mitophagy function, ultimately leading to cell damage (Zhang et al., 2016

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Immunofluorescence staining HFF-1 cells (1.5 10 5 cells per well) or mouse embryonic fibroblasts (NIH3T3) were grown on sterile cell slides for 24 h till 80% confluence