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ShvedovaAAKisinERMurrayARGorelikOArepalliSCastranovaVet al

Astaxanthin has a unique ability to cross the blood-brain barrier as well as the blood-retinalbarrier while most carotenoids do not

The resulting pellet containing restriction enzyme-digested DNA fragments was incubated with 150 M biotin-14-dATP, dCTP, dGTP, and dTTP, and 20 units of Klenow fragment (NEB) at 37 C for 45 min, followed by proximity ligation using 2500 units of T4 DNA ligase (NEB) at room temperature for 4 h with gentle rotation

It was reported by this study that chemical substances are more mutagenic when they are formed by metabolism in bacteria in comparison to rat liver fractions