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Mitochondrial activity is so important that recent studies have revealed that even in embryos that were tested to be genetically normal, mitochondrial defects can lead to poor embryo behavior (faulty division) leading to early losses or failed implantation

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He is a leader in the study of genes that control the aging process

Cells were labeled with 2 M fluorescent nitric oxide indicator DFA-FM DA and fluorescence was detected by fluorescent microscope with a standard fluorescein bandpass filter (FITC, 500555 nm)

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Holst, et al (2011)