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Mechanistically, QAuNP + NIR treatment downregulated the PI3K/AKT/mTOR pathway in HUVECs and reduced nitric oxide (NO) production, contributing to its antiangiogenic effects

In addition, it has been recently demonstrated that, in S

Research has shown that in mice with high oxalate urine and oxalate-stimulated HK-2 cells, there is a significant increase in ROS levels (206), indicating that ferroptosis may be involved in the formation of kidney stones

These diverse observations highlight potential variations in the involvement of SLC38A2 across different pathological subtypes of breast cancer and at various treatment stages, underscoring the need to consider the heterogeneity when targeting SLC38A2 for therapeutic interventions in breast cancer

Yang N, Yao Z, Miao L, Liu J, Gao X, Fan H, Hu Y, Zhang H, Xu Y, Qu A

BSO + MIR-treatment group