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Description

tirzepatide is a dual GIP/GLP-1 incretin agonist a contrast, not an equivalence

Below that shared effect, the molecular stories diverge completely

Cagrilintide gives 1314% weight loss, similar to tirzepatide. That figure comes from CagriSema cagrilintide plus semaglutide not cagrilintide alone

How We Got Here: Development Paths and the CagriSema Caveat The two molecules arrived from different programs

As monotherapy , a multicentre, randomised, double-blind, placebo-controlled and active-controlled Phase 2 dose-finding trial enrolled 706 adults with overweight or obesity (without diabetes) to once-weekly subcutaneous cagrilintide across doses of 0.3 to 4.5 mg over 26 weeks