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In high fat and high sugar model of NAFLD, cassia glycosides can obviously improve liver function and regulate blood lipids when compared with the commonly used drug polyene phosphatidylcholine in clinic, which is related with the inhibition of SREBP-1c expression in liver [112]

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Perfluorooctanesulfonic acid modulates barrier function and systemic T-cell homeostasis during intestinal inflammation

The generation of ROS can adversely affect the structure and function of the GA, potentially leading to modifications in stress signaling pathways downstream ( 9.1 Chondroitin sulfate Chondroitin sulfate, a polysaccharide abundant in the extracellular matrix and on cell surfaces, possesses a sugar chain structure consisting of glucuronic acid and N-acetylgalactosamine (GalNAc) (Figure 14A) (Figure 14B) ( FIGURE 14 2022 Elsevier Ltd

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REDD1 is a gatekeeper of murine hematopoietic stem cell functions during stress responses