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A test set of disease- and non-disease-associated variants To define a set of disease-associated CBS variants, we considered 86 unique missense variants in the CBS mutation database [22] that were not linked to a second variant in the same allele

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Iron storage in ferritin is largely determined by the level of ferritin protein, which is tightly regulated according to cellular iron levels (reviewed in )

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IDO1 inhibitor enhances the effectiveness of PD-1 Blockade in microsatellite stable colorectal cancer by promoting macrophage pro-inflammatory phenotype polarization