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Your Baseline Levels: If you have a deficiency, it may take longer to notice improvements

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Common medications like metformin, acid blockers, and birth control pills deplete B12 levels, so thyroid patients on these drugs need to supplement even more aggressively

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However, the role of BAT PNPLA2 in maintaining thermogenesis has been recently challenged with tissue-specific gene knockout (KO) models

B6 is also involved in over 100 enzyme reactions in the body