Oxidative stress is highly important in this process
10.1105/tpc.110.079145 92 TangZ
An impaired sense of smell can thus be regarded as an early clinical event during disease progression [209, 210]
Embodiment 10 The antibody according to any one of embodiments 1-8, wherein said antibody comprises at least one heavy chain variable region (VH) and at least one light chain variable region (VL), wherein said light chain variable region contains VL CDR1, and/or VL CDR2, and/or VL CDR3 of an antibody selected from the group consisting of M25ADLF, M25ADLFEG, M25ADLFDS, M25FYIA, M25FYIAEG, M25FYIADS, M25, M25EG, M25DS, M25AELF, M25AELFEG, M25AELFDS, M25AELFDS, M25AELFDS, M25ADL99P M25ADL99G, M25ADS95R, M25ADD28G, M25ADS91G, M25ADY93H, M25ADYHSRLF, M25GRITSGFYGDwtLC, M25FSITSGFYGDwtLC, M253018IA, M253018LF, M25AD, M25ADX, ALPPL2rd3_l, ALPPL2rd3_2, M25AGIA, M25AGLF, M25ASIA, M25ASLF, M25ASwt, M25AVIA, M25AVLF, M25ALIA, M25ALLF, M25wtIA, and/or M25wtLF
The accumulation of free radicals in the body overwhelms the natural antioxidant mechanisms, causing oxidative stress, which is linked to the development and progression of NCDs
Evidence-based stewardship focuses on the correct dosage, non-prophylactic use, resistance-based treatment approaches, and selective interventions oriented towards maintaining efficacy, with minimal ecological impact (116119, 139141)
