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It may even be its primary job, Liu says

NAC also improved insulin resistance, suppressed fat from accumulating in the liver, and stimulated thermogenic (fat-burning) genes in the mice, suggesting that NAC may help protect against obesity and obesity-associated metabolic disorders

However, surveys show that there is variability in the tests used to diagnose IMHA (McNeill et al 2019)

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This restoration of metabolic cofactor availability enables enhanced function of NAD+-dependent enzymes including sirtuins, poly(ADP-ribose) polymerases, and various deacetylases that regulate cellular metabolism, stress responses, and aging processes

doi: 10.1016/j.jfutfo.2024.09.006 75 ZhanX.StamovaB.JinL