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Current challenges in NADs development Unlike traditional small molecules and antibody drugs that exert their pharmacological effects on proteins, most NADs directly regulate gene expression, offering a broader range of targets

Standard workplace drug screens do not look for peptides

Despite advancements in metabolomics, which reveal changes in metabolites, a deeper understanding of the biological mechanisms behind these changes and metabolic regulatory processes is still lacking

One study was not original research, which was not obvious from the abstract

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[DOI] [PubMed] [Google Scholar] 93.Solomon B, Varella-Garcia M & Camidge DR ALK gene rearrangements: a new therapeutic target in a molecularly defined subset of non-small cell lung cancer