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Interestingly, the immunological phenomenon of original antigenic sin, where immune responses to subsequent similar but nonidentical antigens are dominated by less effective cross-reactive immunity rather than generating de novo highly specific and effective immunity, has been described for influenza

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A production is influenced by cholesterol levels in neuronal membranes

Finally, we evaluate promising therapeutic approaches targeting this -synferroptosis axis, including aggregation inhibitors, iron chelators, and glial modulators, assessing their potential to alter disease course and address current treatment limitations

Glutathione in defense and signaling