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10.1074/jbc.m109.096099 495 RamachandranJ.BergerA.KatchalskiE

Cortisone is a steroid that is a very powerful anti-inflammatory medication

however, a large cystic structure in the posterior aspect of the calf was identified (Figure 1)

Combination with alpha-lipoic acid enhances pain relief by 10-15%, while discontinuation risks 40-50% symptom recurrence within 4-6 months, emphasizing continuous therapy

This isn't a protocol you just jump into