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As particulates and biofilm accumulate in the media bed, the pressure required to maintain flow increases

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Side Effects: A few possible adverse effects have been reported such as mild gas, diarrhea, and muscle cramps

However, it is important to note that apoptotic cells can release DAMPs even in the absence of critical plasma membrane perturbations, in particular, via secretory lysosomes or exosomes [234, 235]

Clin Chim Acta 530:126133 Lin MH, Cheng PC, Hsiao PJ et al (2023) The GLP-1 receptor agonist exenatide ameliorates neuroinflammation, locomotor activity, and anxiety-like behavior in mice with diet-induced obesity through the modulation of microglial M2 polarization and downregulation of SR-A4