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Cytokines are molecules found on cell membranes that mediate the inflammation, immunity and a range of cellular functions, such as cell differentiation, proliferation, metastasis and apoptosis

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In this study, mice were injected into the ears with either 750,000 or 25,000 human A375 melanoma cells, followed by a 2-day treatment, starting 24 h later, with either saline (control group), ES2 peptide, dabrafenib (a senescence inducer), or a combination of ES2 and dabrafenib [128]