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The catheter, prefilled with 0.9% Sodium Chloride Injection, U.S.P., was fed through the tether system and attached to a swivel secured to the outside of the cage

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In monocyte/macrophage lineages, pharmacological modulation via the metabolic agent metformin achieves dual therapeutic effects by impairing monocyte-to-macrophage differentiation, consequently attenuating age-related macrophage senescence and systemic immune dysfunction

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