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PLoS ONE 7 , e42357 (2012)

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It has been found that mutation in ZnT8 may contribute to dysregulation in insulin in the first passage through the liver and increase risk of type 2 diabetes mellitus development [136]

A growing body of evidence suggests curcumin can positively affect metabolic health and has a potential role in the treatment of metabolic disorders including type 2 diabetes, PCOS, cardiovascular disease, metabolic syndrome, and NAFLD