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Other inhibitors, such as XJB-5-131, dibutyl-hydroxytoluene, and tert-butyl-hydroxyanisole, also inhibit lipid peroxidation and relieve oxidative stress to block ferroptosis, thereby protecting the kidney against various injuries [222]

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In obesity and insulin resistance, mitophagy markers, including LC3BII, Parkin, FUNDC1, and BNIP3, are generally reduced in both human and animal studies, reflecting compromised mitochondrial turnover

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[DOI] [PMC free article] [PubMed] [Google Scholar] 194.Wang L., Fouts D.E., Strkel P., Hartmann P., Chen P., Llorente C., DePew J., Moncera K., Ho S.B., Brenner D., et al