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In the context of this review, similarly as in the other review of borrelial pathogenic mechanisms [8], the term virulence determinants encompasses all genes that impact the infection process, eventhough these factors were often studied and defined in the host animals which are not very susceptible to the disease or show few signs of LD, e.g

Coupling these drawbacks causes physiological jaundice, or high blood bilirubin concentrations, in the first few days of life in fully developed neonates, which is followed by a drop to values typically found in adults during the following few weeks [8]

When growth hormone levels rise, visceral fat breaks down preferentially

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106, 1023 (2015), Abstract Interferon Regulatory Factor-1 signaling regulates the switch between autophagy and apoptosis to determine breast cancer cell fate: J.L