Researchers examine how ligand binding influences receptor activation, downstream signaling propagation, and gene expression patterns
Lavrovsky et al., 1994)
In a high-cholesterol diet male New Zealand White rabbit atherosclerosis model, green tea consumption significantly reduced VEGF expression in foam cells and smooth muscle cells, and it is hypothesized that green tea may slow the progression of atherosclerosis by reducing VEGF-induced angiogenesis (128)
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In addition, mCRP was found to stimulate leukocyte recruitment to the vessel wall, inducing the expression of vascular cell adhesion molecule-1, intercellular adhesion molecule-1, and E-selectin, as well as the production of IL-6 and IL-8 by the endothelium [83]
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