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Where the Science Still Has Gaps Several questions remain unresolved: optimal dosing for therapeutic applications long-term systemic safety standardized clinical protocols large randomized human trials These gaps highlight the difference between promising experimental science and established clinical practice

Liver toxicity would require sustained copper intake far exceeding normal use

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Vandael D, Gounko NV (2019) Corticotropin releasing factor-binding protein (CRF-BP) as a potential new therapeutic target in Alzheimers disease and stress disorders

This makes it an essential component in comprehensive research programs exploring complex biological systems and multi-target therapeutic approaches