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Images were acquired with confocal laser-scanning microscopy (LSM 700, Zeiss) with the same acquisition parameters for the comparison of samples

Finally, we expect that the numerous tool compounds, mechanistic insights, cellular target engagement assays, structural information, and biochemical data we make available will be catalytic for the development of GPX4-inhibiting drugs by the academic and pharmaceutical communities

Obvious immune paralysis occurs in the later stage of sepsis, which often indicates poor prognosis and high mortality (274)

Joachim, Ruhr University Bochum, Germany

10.1016/S2213-8587(19)30151-2 54 KristanD

The activation of EMT appears to be related to specific transcriptional programmes induced by DTPs, with certain transcription factors, such as ZEB1, having a substantial role 102