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Maintaining healthy B12 levels can help you stay sharp and alert, even during busy or stressful times

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Metformin may result in suboptimal oral vitamin B12 absorption by competitively blocking the calcium-dependent binding of the intrinsic factor-vitamin B12 complex to its receptor

Studies with NR supplementation in PD or HF patients have provided indications of impacting mitochondrial function in peripheral tissues, although evidence for impacting mitochondria in the primary target tissues was not reported 318,319

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