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[120] Aronson WJ, Kobayashi N, Barnard RJ, et al

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[52] Inheritance and spontaneous mutation [edit] The mutant gene is transmitted with an autosomal dominant pattern of inheritance, but up to 50% of NF-1 cases arise due to spontaneous mutation

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5.1 Nitrates/Beetroot at Altitude Nitric oxide (NO) is a pleiotropic signaling molecule and a regulator of many physiological and adaptive processes that are endogenously stimulated by hypoxia