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McMahon M, Lamont DJ, Beattie KA, Hayes JD

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A number of factors limit their use in therapeutics, including rapid degradation through nucleases, rapid clearance via renal filtration, and a lack of chemical diversity among others (90)

Under normal conditions, AsA is available mostly in reduced form (Khan et al., 2011)

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However, the natural decomposition is slow and thus the resultant low release of nutrients will limit the agronomic benefits of buried animal by-products and carcasses as a nutrient source for crops or soil improvement