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Phylogenetic analysis revealed that AsGGT3 belongs to a subgroup different from that containing AsGGT1 and AsGGT2 ( Figure 2 ), suggesting that the biochemical characteristics of AsGGT3 might be somewhat different from those of AsGGT1 and AsGGT2

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Further studies with metabolically active MCL-5 cells and chemical inhibitors revealed that the cytotoxicity was related to CYP2E1 and CYP2A6 enzymes

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