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2036-A DEVELOPMENT OF A NOVEL CLINICAL SCREENING TOOL TO PREDICT LIVER FIBROSIS Madeleine Haff 1 , Na Wang 2 , Emily Kate Sisson 2 and Michelle Long 1,3 , (1)Boston Medical Center, Boston, MA, (2)Boston University, (3)Novo Nordisk Background: Nonalcoholic fatty liver disease (NAFLD) is a major contributor to liver disease in the United States, and non-invasive tools such as vibration-controlled transient elastography (VCTE) estimate the risk of liver fibrosis and help guide patient care

[DOI] [PubMed] [Google Scholar] 13.Wu XW, Muzny DM, Lee CC, Caskey CT

" Page 316 and 317: Metcalfe CD, Miao XS, Koenig BG, an Page 318 and 319: generation." Journal of Physical Ch Page 320 and 321: Mimeault C

Additionally, antioxidants hold diagnostic and prognostic value for PF patients

doi:10.1016/j.ymgme.2013.03.011, PMID: 23583222 Salmi H, Leonard JV, Rahman S, Lapatto R (2012) Plasma thiol status is altered in children with mitochondrial diseases

The stability of xCT is regulated by the MUC1-C (Mucin 1 C-terminal subunit)/CD44v (CD44 variant) complex, which directly interacts with xCT to promote its stability and control GSH levels[122]