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Antioxidant treatments tend to decrease the epidermal inflammation by inactivating the free radicals and stabilize the membrane and prevent new epidermal destruction.[] PEMPHIGUS VULGARIS In pemphigus vulgaris, increased production of ROS from activated neutrophils has been found to decrease the concentrations of antioxidants in plasma and RBCs, resulting in oxidative stress

Notably, cholesterol can also act as a signaling molecule

B-complex vitamins particularly B6 and B12 support energy metabolism through mitochondrial pathways and assist in red blood cell production

Jager R, Roberts MD, Lowery RP, Joy JM, Cruthirds CL, Lockwood CM, Rathmacher JA, Purpura M, Wilson JM

[107] used intraperitoneal injection of STZ to construct a DOP model and gave Polygonatum sibiricum polysaccharides via gavage intervention for 48 weeks

[amp]]Beta;-catenin stabilization in skin fibroblasts causes fibrotic lesions by preventing adipocyte differentiation of the reticular dermis